Homura from Madoka Magica! (Even though I can't stand this 雌犬 :D) She freezes time, then while time is frozen, shoots off guns, fires off flame throwers, and bites grenades, then as she she unfreezes time, she walks away from the explosion rising behind her with a dark, unamused scowl on her face
There's soooo many. It's hard to pick one. But Saeko is in my 上, ページのトップへ five for sure with Saya from Blood+, Yourichi from Bleach, エンジェル from エンジェル Beats, and even Dream Eater Merry too. Just soooooo many