but I feel really bad for Callie!
I've recently bought the 秒 series on dvd, because, as I live in England, we're ridiculously behind, and the relationship that stands out for me is Callie/George.
I know a lot of people are all for the Gizzie relationship, but it is debatable whether Izzie and George were actually in love, または whether it was a spur of the moment "we had sex so we need to fall in love" kind-of-thing.
I think the quote that really made me 愛 this couple, correct me if I'm wrong, was from "The Name of the Game" when Callie says that he makes her world stop. And Izzie sums it...
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